Soft Electronic and Microfluidic Systems for the Human Body
适用于人体的柔性电子与柔性微流控系统
Professor John A. Rogers
ABSRACT
Biological tissues are mechanically soft, with complex, time-dependent 3D curvilinear shapes; modern electronic and microfluidic technologies are rigid, with simple, static 2D layouts. Eliminating this profound mismatch in physical properties will create vast opportunities in man-made systems that can intimately integrate with the human body, for diagnostic, therapeutic or surgical function with important, unique capabilities in fitness/wellness, sports performance and clinical healthcare. Over the last decade, a convergence of new concepts in materials science, mechanical engineering, electrical engineering and advanced manufacturing has led to the emergence of diverse, novel classes of 'biocompatible' electronic and microfluidic systems with skin-like physical properties. This talk describes the key ideas and presents some of the most recent device examples, including (1) wireless, battery-free electronic 'tattoos', with applications in continuous monitoring of vital signs in neonatal and pediatric intensive care, including active deployments in the most advanced hospitals in the US and clinics in multiple countries in Africa and (2) microfluidic platforms that can capture, manipulate and perform biomarker analysis on microliter volumes of sweat, with applications in precise hydration management in sports and fitness, including commercial devices featured on celebrity sports figures with Gatorade. The presentation will feature the most recent results from the group, with highlights in published and unpublished work over the last three months.
生物组织具有柔性、复杂的三维形貌，且随时间不断变化；而目前的电子与微流控系统具有刚性、简单的平面结构。如果能消除生物组织与电子、微流控系统在物理性质上的种种差异，则可以使这些人工系统与人体无缝集成，提供多种多样的检测、治疗功能，从而广泛应用在健身、健康、体育运动、临床试验等诸多领域。近年来，通过综合材料科学、力学、电子学以及先进制造技术，一系列具有生物兼容性、且在物理性质上与人体皮肤类似的柔性电子与柔性微流控系统已经被研发出来。本报告将介绍课题组近年来的一些核心技术和概念，包括（1）无需电池的无线电子纹身，具有临床级别的生命体征信号检测能力，且已经被应用于美国的新生儿及儿科重症监室以及非洲的部分国家；（2）柔性微流控系统，可以获取、控制并分析微升级别的汗液，且已经被应用于于运动与健身中的精确的人体水分管理，商业化的器件得到了知名运动员及佳得乐公司的支持与推广。本报告将介绍课题组最新的研究进展，突出近三个月内已经发表和未发表的成果。
BIOGRAPHY
Professor John A. Rogers, Northwestern University, the Louis Simpson and Kimberly Querrey Professor of Materials Science and Engineering, Biomedical Engineering, Mechanical Engineering, Electrical Engineering and Computer Science, Chemistry and Neurological Surgery, where he is also the founding Director of the newly endowed Center on Bio-Integrated Electronics.
Rogers’ research has been recognized with many awards including, most recently, the Benjamin Franklin Medal from the Franklin Institute (2019), the MRS Medal from the Materials Research Society (2018), the Samuel R. Natelson Award from the American Association for Clinical Chemistry (2018), the Nadai Medal from the American Society of Mechanical Engineers (2017), the IEEE EMBS Trailblazer Award (2016), the ETH Zurich Chemical Engineering Medal (2015), the A.C. Eringen Medal from the Society for Engineering Science (2014), the Smithsonian Award for American Ingenuity in the Physical Sciences (2013), the Robert Henry Thurston Award from the American Society of Mechanical Engineers (2013), the Mid-Career Researcher Award from the Materials Research Society (2013), the Lemelson-MIT Prize (2011), a MacArthur Fellowship from the John D. and Catherine T. MacArthur Foundation (2009), the George Smith Award from the IEEE (2009), the National Security Science and Engineering Faculty Fellowship from the Department of Defense (2008), the Daniel Drucker Eminent Faculty Award from the University of Illinois (2007) and the Leo Hendrick Baekeland Award from the American Chemical Society (2007). Rogers is a member of the National Academy of Engineering (NAE; 2011), the National Academy of Sciences (NAS; 2015), the National Academy of Medicine (NAM; 2019) and the American Academy of Arts and Sciences (AAAS; 2014), a Fellow of the Institute for Electrical and Electronics Engineers (IEEE; 2009), the American Physical Society (APS; 2006), the Materials Research Society (MRS; 2007), the American Association for the Advancement of Science (AAAS; 2008) and the National Academy of Inventors (NAI; 2013). He received an Honoris Causa Doctorate from the Ecole Polytechnique Federale de Lausanne (EPFL), and holds Honorary Professorships at Fudan University, Shanghai Jiaotong University and Zhejiang University.
约翰 A 罗杰斯教授于1989年本科毕业于德克萨斯州大学奥斯汀分校，获物理化学学士学位；1992年硕士毕业于MIT，获物理化学硕士学位；1995年博士毕业于MIT，获物理化学博士学位。1995-1997年，罗杰斯教授获得了哈佛大学Junior Fellow的资助。在此期间，罗杰斯教授同时成立了Active Impulse Systems公司，用于产业化他博士期间开发的一些列技术。罗杰斯教授在1997年加入贝尔实验室，担任凝聚态物理研究部门的技术员，并在2000-2003年担任该部门的主任。2003-2016年，罗杰斯教授任职于伊利诺伊大学厄巴纳-尚佩恩分校，担任Swanlund讲席教授（该校最高荣誉），主要任职于材料科学工程系，并在化学系、生物工程系、机械工程系、电子与计算机工程系兼职，同时担任担任纳米科学与工程中心-纳米加工分部的主任。2009-2012年，罗杰斯教授担任Seitz材料实验室主任。罗杰斯教授于2016年9月加入西北大学，担任Louis Simpson与Kimberly Querrey教授，任职于材料科学与工程系、生物医学工程系、机械工程系、电子与计算机工程系、化学系、以及神经外科系，同时担任生物集成电子中心主任。
罗杰斯教授的研究方向微米纳米加工技术、电子光电子器件、生物集成系统等。他已经发表超过650篇论文，获得了超过70项专利授权并在各大公司及他所创建的多个初创公司广泛使用。罗杰斯教授为美国工程院院士（2011）、美国科学院院士（2015）、美国医学院院士（2019）、美国文理科学园院士（2014），电气电子工程师学会会士（IEEE, 2009）、美国物理学会会士（2006, APS）、材料研究会会士（MRS, 2007）、美国科学促进会会士（AAAS, 2008）、美国国家发明家学会会士（NAI, 2013）,获得的奖项包括： Benjamin Franklin 奖章（2019），MRS奖章（2018），Samuel R. Natelson奖（2018），Nadai奖章（2017）IEEE EMB